Low Platelets or ITP Blood Disorder New Drug
Pharmaceutical Business Review wrote:
Revolade, an oral platelet generator is used to treat thrombocytopenia (reduced platelet count) in adults with the blood disorder chronic immune (idiopathic) thrombocytopenic purpura (ITP) who have had an insufficient response to corticosteroids …
See all stories on this topic »
Comments: New drug now in oral form Revolade also known as Eltrombopag olamine tablets is being promoted for chronic ITP Blood disorder in those who do not respond well to Prednisone. But did you know that this drug also known as Promacta can cause cancer, scarring and permanent damage to the bone marrow, liver damage, clot formation? If this doesn’t scare you what will? Anyway, I’ll stay with the natural approach!
Thrombocytopenia – Ligand Pharmaceuticals Announces Second Quarter Results
MarketWatch (press release) wrote:
Ligand partner GlaxoSmithKline announced that it received positive data from ENABLE-1, the first of two Phase III studies examining Promacta (eltrombopag) in patients with hepatitis C-related thrombocytopenia, and that full data will be released at an …
See all stories on this topic »
Comments: Even though there are some positive reports at the end of this article, it seems that they are more concentrated at the revenue and the stock market. It makes you want to think if the interest of those suffering from this disease is whats really in their mind.
Thrombocytopenia – Ligand Pharmaceuticals Announces Second Quarter Results
MarketWatch (press release) wrote:
Ligand partner GlaxoSmithKline announced that it received positive data from ENABLE-1, the first of two Phase III studies examining Promacta (eltrombopag) in patients with hepatitis C-related thrombocytopenia, and that full data will be released at an …
See all stories on this topic »
Comments: Even though there are some positive reports at the end of this article, it seems that they are more concentrated at the revenue and the stock market. It makes you want to think if the interest of those suffering from this disease is whats really in their mind.
Immune Mediated – Thrombocytopenia
The definition of thrombocytopenia is a low platelet count. Many diseases can cause the platelet count to decrease including Ehrlichia, Rocky Mountain …
www.thewebpetdr.com/…/immune-mediated-thrombocytopeni…
Comments: Here is another well written but concise explanation of what immune mediated thrombocytopenia is. It is a simple but definitive explanation of what it is.
Is the World Really Ending Today?
Check this interview in Fox channel online to hear the truth about this. I just shared a video with you from http://www.fox40.com Here is the Link: http://www.fox40.com/videobeta/65e3f56e-4505-4d0e-9cdc-b20038cdf48b/News/Doomsday-May-21st-Pastor-Doug-Batchelor Want to know the truth about the Second coming of Christ without extreme positions go to: http://www.bibleuniverse.com/articles/second-coming-prophecies-fulfilled/the-glorious-hope.aspx
Being careful with personal remedies for thrombocytopenia
For that reason you should not just take any remedy that you hear or read online without really knowing what you are doing.f
Consider checking your vitamin D levels. Many times when this vitamin is low it can cause thrombocytopenia in people who are already predisposed to it.
Also don’t try to take a supplement without changing your lifestyle. Eight hours of sleep daily, reduction of stress, mild exercise daily, taking the correct supplements and herbal products can make a big difference towards normalizing your low platelet count and getting rid of itp blood disorder.
Also do not believe all the bad rap that people online give to herbal products. They really do not know what they are talking about.
And many sites even though they may seem reputable, over exaggerate the side effects they give to herbs making them seem so dangerous while they themselves are recommending known toxic drugs.
Any way, til later
Thrombocytopenia: Sarcoidosis as a cause of Low Platelets
As early as 1952 Sarcoidosis (an autoimmune disease that produces granuloma in different organs but especially the lungs) patients have been found ( a small group) to develop thrombocytopenia.
It is of no surprise since ITP blood disorder is caused by an autoimmune reaction as is Sarcoidosis. But in many cases of Thrombocytopenia caused by Sarcoidosis the culprit has been two factors:
1) the granulomas caused by the disease have attacked the bone marrow
2) Hypersplenism – a condition in which the spleen enlarges and become over-active in it’s destructive functions on platelets
The treatment of preference has been steroids (prednisone). In another group of sarcoidosis Immune thrombocytopenia also known as ITP is developed. In either case the treatment is the same – Prednisone. In a small amount of cases Rituximab has been used with some level of sucess.
Herbal remedies have been found to be beneficial for those suffering from thrombocytopenia due to ITP. And since the medical treatment is the same in this case, there is little doubt that herbal remedies may also benefit those who develop ITP due to Sarcoidosis.
Many of the herbal remedies recommended for Thrombocytopenia work by:
1) Their steroid-like effects on the body and by preserving the body’s own production of steroids by the adrenal glands.
2) By calming down the immune system so it stops attacking the platelets
3) Detoxification
In some cases the person will benefit by combining both conventional and natural therapies.
Always consult your doctor and let them know that you plan to use natural herbal remedies (even though most doctors know very little about them).
Always check your levels of Vitamin D since this can be an issue in some cases. Many people have very low levels of Vitamin D and this tends to cause an aggressive immune system that attacks platelets.
Thrombocytopenia: New Extended Chapters added to Conquer Low Platelets
Hi everyone!! Just wanted to let you know that Some extended chapters has been added to Conquer Low Platelets.
The added information is like a response to some of the major concerns that many who purchased the ebook had.
Some of the questions answered are:
1) Thrombocytopenia during Pregnancy
2) Does Papaya leaf really work
3) How to adjust the dosage of herbs to children
Plus other important questions are answered.
As more info comes in…I will be adding more to this ebook.
God bless!
PS For those who have purchased the ebook in the past …can send me your receipt number and email and I will send you the update.
Louis Cruz
Conquer Low Platelets
- Posted using BlogPress from my iPad
Thrombocytopenia: Caused by a reaction to Heparin Sodium
Editors comments: These are one of the circumstances where medical treatment is needed if Thrombocytopenia occurs. Even though in the article it talks about the problem as easy to resolve after the drug heparin sodium is discontinued….the reality is that some may develop serious side effects that are not only manifested as Thrombocytopenia but some times also as DIC (Disseminated intra-vascular coagulation) and when these two conditions are combined it becomes a serious situation to treat.
At this point when this happens, you must make sure that you are under continual medical supervision (hospitalized) and treated accordingly. At this point no natural remedy is known in this severe case.
On the contrary, Thrombocytopenia due to ITP, Leukemia, Pregnancy and other causes can many times respond to natural remedies.
by Anil Kumar
A serious side-effect of heparin is heparin-induced thrombocytopenia (HIT). HIT is caused by an immunological reaction that makes platelets a target of immunological response, resulting in the degradation of platelets.
Heparin sodium allergy may present with bruising, particularly purpura in the forearms, petechia (pinpoint hemorrhages on skin and mucous membranes), nosebleeds and/or bleeding gums.
This condition is usually reversed on discontinuation. There is also a benign form of thrombocytopenia associated with early heparin use, which resolves without stopping heparin.
There are two nonhemorrhagic side-effects of heparin treatment. The first is elevation of serum aminotransferase levels, which has been reported in as many as 80% of patients receiving heparin. This abnormality is not associated with liver dysfunction, and it disappears after the drug is discontinued. The other complication is hyperkalemia, which occurs in 5 to 10% of patients receiving heparin, and is the result of heparin-induced aldosterone suppression. The hyperkalemia can appear within a few days after the onset of heparin therapy. More rarely, side-effects include alopecia and osteoporosis can occur with chronic use.
As with many drugs, overdoses of heparin can be fatal. In September 2006, heparin received worldwide publicity when 3 prematurely-born infants died after they were mistakenly given overdoses of heparin at an Indianapolis hospital. Protamine sulfate (1 mg per 100 units of heparin that had been given over four hours) has been given to counteract the anticoagulant of heparin.
This article was written by Anil Kumar from the following site: http://www.healthnewstrack.com/health-news-2516.html
Immune Thrombocytopenia – Drug Finally Approved
Comments: Even though many people don’t know about it but there are many positive studies that indicate that herbal remedies may also be effective in helping Thrombocytopenia. Many don’t know about them. You can find a lot of these studies in the e-book Conquer Low Platelets. But I am also happy they the medical establishment is also trying their best to provide alternatives for sufferer of Low Platelets
NICE Gives Green Light To Romiplostim For The Treatment Of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP) from http://www.medicalnewstoday.com/articles/219417.php
The National Institute for Health
and Clinical Excellence (NICE) has recommended romiplostim (Nplate, Amgen) for the treatment of chronic immune (idiopathic[1]) thrombocytopenic purpura (ITP) in some patients in draft guidance issued yesterday (Thursday 17 March 2011).
ITP is a bleeding disorder in which the immune system destroys platelets, which are needed for normal blood clotting. People with the disease have abnormally low levels of platelets in the blood. The condition is currently thought to affect 3000 – 3500 people in the UK; some patients may only have the condition for a short period of time, but when a patient has ITP for over 12 months this is defined as having chronic ITP.
In this draft guidance, romiplostim is recommended for the treatment of adults with chronic ITP:
- whose condition does not respond to standard active treatments and rescue therapies or,
- who have severe disease, and a high risk of bleeding that requires frequent courses of rescue therapies, and
-if the manufacturer makes romiplostim available with the rebate on the list price agreed under the patient access scheme.
Only a haematologist should initiate and supervise treatment with romiplostim. The recommendations are conditional on the manufacturer providing romiplostim at a discounted cost as part of a patient access scheme[2].
NICE has not yet issued final guidance to the NHS; consultees now have the opportunity to appeal against this final draft guidance.
Dr Carole Longson, Director, Health Technology Evaluation Centre at NICE said: “ITP is a serious, sometimes debilitating disorder, and some of the current treatments have considerable side effects, so we are pleased to recommend the use of romiplostim as a clinically and cost effective treatment for some people with severe, chronic ITP in our draft guidance issued today. The manufacturer has also submitted a patient access scheme where the cost of the treatment will be reduced.”
The draft guidance is available from Thursday 17 March until Thursday 31 March.
Consultees now have the opportunity to appeal against this draft guidance. If there are no appeals, or an appeal is not upheld, the recommendations in the draft will be issued as final NICE guidance. NICE expects to issue final guidance to the NHS in April 2011. Until this time, NHS bodies should make decisions locally on the funding of specific treatments. Once NICE issues its final guidance on a technology, it replaces local recommendations across the country.
Final guidance is likely to be published in April 2011.
[1] Of unknown cause.
[2] Patient access schemes are ways pharmaceutical companies can propose to enable patients to gain access to high cost drugs.
- Romiplostim for Treatment on Immune Thrombocytopenia (ITP)
- Nplate (romiplostim) for ITP
- NICE Gives Green Light To Romiplostim For The Treatment Of Chronic Immune (Idiopathic) Thrombocytopenic Purpura (ITP)
- Amgen to acquire BioVex as sales rise – Pharma Times
- How come I am bruising on my legs so often?
- Amgen Establishes Commercial Operations In Brazil
- Can diet affect platelet count?
- Possible new approach to treating a life-threatening blood disorder